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Diphenhydramine is an antihistamine medicine that relieves the symptoms of allergies. It’s known as a drowsy (sedating) antihistamine and is more likely to make you feel sleepy than other antihistamines. It’s used for:
- short-term sleep problems (insomnia), including when a cough, cold or itching is keeping you awake at night
- cough and cold symptoms
- hay fever
- eczema, hives (urticaria) and insect bites and stings
You can buy diphenhydramine from pharmacies and it is also available on prescription.
It comes as tablets and a liquid that you swallow. For skin allergies like hives or bites and stings it’s also available as a cream. The cream is much less likely to make you feel sleepy than the tablets or liquid.
You can also buy it mixed with other medicines, such as levomenthol, paracetamol and pseudoephedrine, to treat cough and cold symptoms.
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