P-5-P 50mg

Pyridoxal-5-phosphate (P-5-P, also written PLP) is the active coenzyme form of Vitamin B6 — the form actually used by the body’s enzymes. Standard B6 supplements use pyridoxine HCl, which the liver has to convert into P-5-P before the body can use it. By supplementing with P-5-P directly, the conversion step is bypassed.

P-5-P is involved in over 100 enzyme reactions in the body, particularly those of amino acid metabolism. It is required for the synthesis of several neurotransmitters including serotonin, dopamine, GABA and noradrenaline, and works as a cofactor with folate and B12 in homocysteine metabolism.

Each tablet provides 50mg of P-5-P, delivering 34mg of Vitamin B6. Long-term high-dose B6 supplementation (typically above 200mg daily over extended periods) has been associated with peripheral nerve effects in some individuals. The UK Government’s Scientific Advisory Committee on Nutrition guideline for prolonged use is below 10mg/day; this product is intended for shorter-term use.

Approved EFSA Health Claims for Vitamin B6:

• Contributes to normal cysteine and homocysteine synthesis and metabolism
• Contributes to normal energy-yielding metabolism
• Contributes to the normal functioning of the nervous system
• Contributes to normal psychological function
• Contributes to the reduction of tiredness and fatigue
• Contributes to the regulation of hormonal activity

Made in the UK. Take one tablet daily with a meal.