Varenicline (Champix®)

Buy Champix® Online

Varenicline (branded as Champix®) is a prescription-only medication clinically proven to help adults stop smoking by reducing cravings and withdrawal symptoms. This private pharmacy service allows motivated individuals to begin treatment without visiting a GP, with pharmacist-led support to ensure safe and effective use.

Active Ingredient

Varenicline tartrate

Patient Leaflet Information

Directions

Dosage Schedule:

• Days 1–3: 0.5 mg once daily
• Days 4–7: 0.5 mg twice daily
• Day 8 onward: 1 mg twice daily (continue for remainder of 12-week course)

Administration:

Take tablets whole with water at the same times each day, preferably after food.

Course Duration:

12 weeks (with an optional second 12-week maintenance course if advised by your pharmacist)

Supply Format:

Initial supply: 2 weeks

Follow-up supplies: 4 weeks (x2) + final 2-week course

Important:

You must set a quit date between days 8–14 of starting Varenicline. Abstain completely from smoking by this date.

About Varenicline

What is Varenicline (Champix®)?

Varenicline is a stop-smoking aid that works by binding to nicotine receptors in the brain. This blocks the pleasurable effects of nicotine while easing withdrawal symptoms, making it easier to quit smoking for good.

How Varenicline Works

Varenicline is a partial nicotine receptor agonist.

It:

• Mimics the effects of nicotine to reduce cravings
• Blocks nicotine from activating reward pathways if you smoke
• Helps reduce relapse by controlling withdrawal symptoms and satisfaction from smoking

Understanding the Condition

What is nicotine addiction?

Nicotine addiction occurs when repeated tobacco use causes physical dependence and behavioral habits. Withdrawal can include irritability, anxiety, strong cravings, and difficulty concentrating. Varenicline addresses both physical and psychological aspects of quitting.

Product Compatibility

Can Varenicline be taken with other medications?

You should not take Varenicline with:

• Bupropion (Zyban®)
• Isotretinoin or psychiatric medications that lower seizure threshold
• Other smoking cessation products, unless specifically advised
• Always inform your pharmacist of any current medications before starting this treatment.

Safety During Pregnancy and Breastfeeding

Do not use Varenicline if pregnant, planning pregnancy, or breastfeeding. Speak with your doctor or pharmacist for safer alternatives.

Precautions

Do not use if:

• Under 18 years of age
• Pregnant or breastfeeding
• You have a history of psychiatric illness (including suicidal thoughts)
• You have severe kidney impairment (eGFR < 30ml/min)
• You have seizure risk or are taking medicines that lower seizure threshold
• You are allergic to Varenicline or any of its ingredients

Possible Side Effects

Common:

• Nausea (most frequent)
• Insomnia or vivid dreams
• Headache
• Dry mouth

Less Common:

• Mood changes, irritability, or depression
• Sleep disturbances

Rare but serious:

• Allergic reactions (rash, swelling, breathing difficulties)
• Hallucinations or severe behavioral changes

Stop treatment and seek immediate help if these occur.

Storage Instructions

Store below 25°C

Keep in original packaging

Keep out of sight and reach of children

Support Provided

• One-to-one consultations with a pharmacist
• Quit date setting and progress tracking
• Managing triggers and preventing relapse
• Supportive mental health and lifestyle advice

Need help?

Questions about this medicine? Contact the pharmacy team on 020 8106 7084 or through the contact form on this website. Our GPhC-registered pharmacists answer clinical questions through our official channels only.